FCS Express has a complete set of functionality to allow you to electronically sign your documents, a necessary features for CFR 21 Part 11 Compliance. FCS Express allows you to create as many signatures as you wish.
As you can see in the figure below, three different signatures have been defined. You can also choose which security groups are allowed to sign a particular signature. For instance, in the figure above, only members of the Pathologist group are allowed to approve the layout.